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"House, also titled House, M.D., is an American television series. It is an hour-long medical drama that debuted in the fall of 2004 and stars Emmy-nominated and Golden Globe-winning British actor and comedian Hugh Laurie. Laurie plays Dr. Gregory House, a maverick medical genius who heads a team of young diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. This team goes to extraordinary lengths to accomplish a common task: diagnosing and treating unusual ailments. Most episodes start outside the hospital, showing the events leading to the onset of illness for that week's patient.

Dr. House's begrudging fulfillment of his mandatory clinic duty is a recurring subplot on the show. During clinic duty, House confounds patients with his eccentric bedside manner and often unorthodox treatments, but impresses them with rapid and accurate diagnoses after seemingly not paying attention. In one episode, House diagnoses an entire waiting room full of patients on his way out of the clinic. Often, some of the simpler problems House faces in the clinic help him solve the main case of the show.

Many of the illnesses and conditions encountered during the series could have been solved earlier if the patient/patients' families had not lied or hidden other symptoms (lying about having an affair that led to the mystery disease, lying about an underlying disorder, lying about jobs that lead to the mystery disease, and so on), thus every episode lends more and more backing to House's beloved stock phrase, "Everybody Lies".

Several episodes feature the unusual practice of entering a patient's house with or without their permission in order to search for clues that might suggest a certain pathology. The creator, David Shore, originally intended for the show to be an "ER meets CSI" type show, but has since shifted some of the focus to the characters rather than focusing solely on the plot."

From: Wikipedia